Département de neurosciences: conférence du vendredi midi

Impact of neocortical inhibitory neurons on cortical processing and behavior

Renata Batista-Brito, PhD
Assistant Professor of Neuroscience, and Genetics
Albert Einstein College of Medicine, NY, USA

Résumé:
My laboratory’s research interests focus on understanding how the development of specific neuronal cell types, and associated circuits, orchestrates the proper maturation and function of the cortex and how even mild changes in neuronal activity during early life can result in profound alterations in the brain later in life. We are particularly interested in understanding the mechanistic circuits underlying contextual modulations in health and in neurodevelopmental disorders. We focus on contextual influences of global behavioral/arousal state (e.g. how alert am I? how rested am I), sensory predictions (e.g. which stimuli do I expect?), and top-down attention (what is relevant to me?). These operations are implemented throughout sensory cortices, and are mediated by excitatory and inhibitory neocortical circuits, however the specific nature of those circuits, how do they mature during childhood and how they impact autism-spectrum disorders remains largely unknown.

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Ce contenu a été mis à jour le 18 avril 2023 à 20 h 47 min.